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Pharmaceuticals | Free Full-Text | Opioid Analgesia and Opioid-Induced Adverse Effects: A Review
Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics | Hypertension
Breaking barriers to novel analgesic drug development | Nature Reviews Drug Discovery
The Role of Peripheral Opioid Receptors in Triggering Heroin-induced Brain Hypoxia | Scientific Reports
Synthesis and Structure–Activity Relationships of 5′-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects | Journal ...
Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist
Frontiers | The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia
Synthesis and Structure–Activity Relationships of 5′-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects | Journal ...
Molecules | Free Full-Text | Mechanistic Characterization of the Pharmacological Profile of HS-731, a Peripherally Acting Opioid Analgesic, at the µ-, δ-, κ-Opioid and Nociceptin Receptors
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience
Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
The receptor hypothesis and the pathogenesis of depression: Genetic bases and biological correlates - ScienceDirect
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience
Antagonists of the kappa opioid receptor - ScienceDirect
Frontiers | Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors
Dynamic lateral organization of opioid receptors (kappa, muwt and muN40D) in the plasma membrane at the nanoscale level - Rogacki - 2018 - Traffic - Wiley Online Library
Frontiers | Advances in Achieving Opioid Analgesia Without Side Effects
Kappa Opioid Receptor Activation Potentiates the Cocaine-Induced Increase in Evoked Dopamine Release Recorded In Vivo in the Mouse Nucleus Accumbens | Neuropsychopharmacology
Putative interaction modes of morphine-based high-affinity... | Download Scientific Diagram
Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological Activity | Journal of Medicinal Chemistry
Nanobody-enabled monitoring of kappa opioid receptor states | Nature Communications
Ethanol and Naltrexone Have Distinct Effects on the Lateral Nano-organization of Mu and Kappa Opioid Receptors in the Plasma Membrane | ACS Chemical Neuroscience
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect
A Phase 3 Trial of Difelikefalin in Hemodialysis Patients with Pruritus | NEJM
Lion's Mane contains kappa agonist - Supplements - LONGECITY